Active trials

Read more about the active trials that MedVadis Research is involved with. Contact us anytime if you would like to volunteer or have any questions.

Adult Migraine

Study ID 273

SPRINT® Peripheral Nerve Stimulation for the Treatment of Head Pain

Treatment of Head Pain With the SPRINT® Peripheral Nerve Stimulation (PNS) System

Medical Conditions:

Cervicogenic Headache | Occipital Neuralgia

Related Conditions: Cervicogenic Headache | Occipital Neuralgia

Sex/Gender: All

Age: 21+

Enrolling now!

Study ID ABC

Extension Study of ABP-20001 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 for Migraine Prevention

This Phase 2 Extension trial will evaluate the efficacy and safety of ABP-450 for migraine prevention in adults who suffer from six or more migraine days per month. The study will enroll approximately 666 patients across approximately 65 sites in the United States, Canada and Australia from the Phase 2 trial. Study subjects will be divided evenly across a low dose group and a high dose group. All patients will receive four treatment cycles of ABP-450 utilizing the Company's novel injection paradigm.

Medical Conditions:

Migraine

Related Conditions: Migraine

Sex/Gender: All

Age: 18+

Enrolling now!

ALS

Study ID 265

A Single-Site Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and preventative methods for specific and complex conditions.

Medical Conditions:

Age-Related Macular Degeneration | Allergies | Alpha-Gal Syndrome | Alzheimer Disease

Related Conditions: Age-Related Macular Degeneration | Allergies | Alpha-Gal Syndrome | Alzheimer Disease

Sex/Gender: All

Age: 18-85yrs

Enrolling now!

Study ID 259

Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease (REGEN-BRAIN©)

Safety and Efficacy of Allopregnanolone (Allo) as a Regenerative Therapeutic for Alzheimer's Disease: Multicenter, Double-Blind, Randomized, Placebo-Controlled, Phase 2 Clinical Trial

Medical Conditions:

Alzheimer Dimentia | Late Onset Alzheimer's Disease | Neurodegenerative Disease

Related Conditions: Alzheimer Dimentia | Late Onset Alzheimer's Disease | Neurodegenerative Disease

Sex/Gender: All

Age: 55-80yrs

Enrolling now!

Alzheimer’s Disease

Study ID 267

A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)

A Study of Remternetug Versus Placebo in Early Alzheimer's Disease Participants at Risk for Cognitive and Functional Decline

Medical Conditions:

Alzheimer's Disease

Related Conditions: Alzheimer's Disease

Sex/Gender: All

Age: 55-80yrs

Enrolling now!

Chronic Knee Pain

Study ID 501

Placeholder Chronic Knee Pain to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

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Medical Conditions:

Chronic Knee Pain

Related Conditions: Chronic Knee Pain

Sex/Gender: Female

Age: 18+

Enrolling now!

Chronic Low Back Pain

Study ID 523

Chronic Low Back Pain Placeholder for Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

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Medical Conditions:

Chronic Low Back Pain

Related Conditions: Chronic Low Back Pain

Sex/Gender: Male

Age: 34+

Enrolling now!

Diabetic Neuropathy

Study ID 295

Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabetic peripheral neuropathy (DPN).

Medical Conditions:

Diabetic Neuropathy

Related Conditions: Diabetic Neuropathy

Sex/Gender: All

Age: 18-80yrs

Enrolling now!

Study ID 268

A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic Pain (NEPTUNE-17)

This is a multicenter randomized, double-blind, placebo-controlled phase 2 study to evaluate efficacy, safety, tolerability, pharmacokinetics, and target engagement of GSK3858279 in adult participants with chronic Diabetic Peripheral Neuropathic Pain (DPNP). The primary objective of the study is to assess the efficacy of GSK3858279 in participants with DPNP who have been unable to sufficiently manage their pain.

Medical Conditions:

Diabetic Neuropathy

Related Conditions: Diabetic Neuropathy

Sex/Gender: All

Age: 18-75yrs

Enrolling now!

Obesity

Study ID 299

Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Retatrutide once weekly in participants who have obesity or overweight and chronic low back pain (TRIUMPH-7)

Medical Conditions:

Obesity

Related Conditions: Obesity

Sex/Gender: All

Age: All

Enrolling now!

Study ID 279

A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight (TRIUMPH-2)

The purpose of this study is to is to evaluate the efficacy and safety of retatrutide in participants with type 2 diabetes in participants who have obesity or overweight (J1I-MC-GZBK master protocol) including a subset of participants who have obstructive sleep apnea (OSA) (J1I-MC-GSA2). The study will last about 89 weeks and will include up to 24 visits.

Medical Conditions:

Obesity | Overweight | Type 2 Diabetes | Obstructive Sleep Apnea

Related Conditions: Obesity | Overweight | Type 2 Diabetes | Obstructive Sleep Apnea

Sex/Gender: All

Age: 18+

Enrolling now!

Pediatric Migraine

Study ID 249

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

The purpose of this study is to test the long-term safety of rimegepant in the acute treatment of moderate or severe migraine in children and adolescents (≥ 6 to < 18 years of age).

Medical Conditions:

Acute Treatment of Migraine

Related Conditions: Acute Treatment of Migraine

Sex/Gender: All

Age: 6-17yrs

Enrolling now!

Study ID 242

A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine (PIONEER-PEDS2)

The reason for this 12-month, open-label study is to see if the study drug lasmiditan is safe and effective for the intermittent acute treatment of migraine in children aged 6 to 17. The study will last about 12 months and may include up to 7 visits.

Medical Conditions:

Migraine

Related Conditions: Migraine

Sex/Gender: All

Age: 6-17yrs

Enrolling now!

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